Subtype-dependent response of hepatitis B virus during the early phase of lamivudine treatment.

نویسندگان

  • Bernhard Zöllner
  • Jörg Petersen
  • Peter Schäfer
  • Matthias Schröter
  • Rainer Laufs
  • Martina Sterneck
  • Heinz-Hubert Feucht
چکیده

We conducted a 12-month longitudinal investigation of the subtype-dependent response of hepatitis B virus (HBV) to lamivudine treatment in 43 consecutive patients with chronic hepatitis B. HBV subtype ayw appears to respond better to lamivudine monotherapy than does HBV subtype adw (P=.005). This might be the reason for the lower incidence of lamivudine-resistant strains observed in persons infected with HBV subtype ayw during follow-up.

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عنوان ژورنال:
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

دوره 34 9  شماره 

صفحات  -

تاریخ انتشار 2002